The recommended dose is 1 tablet in the morning and 1 in the evening (1 every 12hrs). The full treatment is for 3 months, if the symptoms have gotten better by then you can lower the dose to 1 tablet everyday for 1 week and after that 1 every other day depending on how you feel.
Since it has a light energizing effect it is not recommended to have it before going to bed specially if you have problems with insomnia.